Clinicopathological Spectrum of Benign Lesions of Larynx: A Prospective Observational Study
Main Article Content
Abstract
Abstract:
Introduction: Every human voice is unique because of anatomical, physiological, cultural, sociolinguistic and behavioural factors. Any disorder interfering with approximation, tension or vibration of vocal cord will change the quality, pitch and loudness of voice. The objective was to study the clinical profile, histopathological patterns and treatment options of benign lesions of larynx.
Materials and Methods: A prospective observational study was conducted for 80 cases clinically diagnosed as benign lesions of larynx. The inflammatory lesions were treated by conservative medical and speech therapy. Surgical intervention was done for neoplastic lesions of vocal cord.
Results: In our study, majority of patients 28(35%) were between 21-30 years of age. Male preponderence was seen. Voice abuse in 53 cases was the common predisposing factor. The most frequent symptom Hoarseness or voice change together constituted 66(82.5%), followed by vocal fatigue. Vocal cord polyp was the most frequent benign lesion in 17(21.25%) patients, followed by vocal cord nodule in 14, chronic laryngitis in 8 and vocal cord palsy in 7 patients. Microlaryngeal surgery was done in 49 patients.
Conclusion: The vocal cord polyp is the commonest benign laryngeal lesions producing hoarseness of voice as the chief complaint. There was a high correlation between clinical and pathological diagnosis of benign lesions of larynx.
Article Details
Section

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
References
References:
Robin PE, Olofsson J. Tumours of the larynx. In: Hibbert J Laryngology and head and neck surgery, 6th edn. Heinemann International, Great Britain, 1997; 1–9.
Hollinger PH, Johnston KC. Benign tumors of the larynx. Ann Otol 1951;60:496-509.
Winston P, Epstein SS. Papilloma of the larynx: A clinicopathological study. J Laryngol Otol 1958;72:452-64.
Sataloff RT, Ressue JC, Portell M, Harris RM, Ossoff R, Merati AL, et al. Granular cell tumors of the larynx. J Voice Mar 2000;14(1):119-34.
Johns MM. Update on the etiology, diagnosis andtreatment of vocal fold nodules, polyps and cysts. CurrOpinOtolaryngol Head Neck Surg 2003; 11(6):456–61.
Rosen CA, Simpson CB. Operative Techniques in Laryngology. 1st ed. New York, NY: Springer; 2008: 63-75.
Rosen CA, Lee AS, Osborne J, Zullo T, Murry T. Development and validation of the Voice Handicap Index-10. Laryngoscope 2004;114:1549–1556
Hegde MC, Kamath PM, Bhojwani K, Peter R, Babu PR. Benign lesions of the larynx: A clinical study. IJLO 2005;57(1):35-38.
Singhal P, Bhandari A, Chouhan M, Sharma MP, Sharma S. Benign tumors of the larynx: A clinical study of 50 cases. IJLO 2009;61(1):26-30.
Wani AA, Rehman A, Hamid S, Akhter M, Baseena S. Benign Mucosal Fold Lesion as a Cause of Hoarseness of Voice. A Clinical Study. Otolaryngol 2012; 2(3):120.
Batra K, Motwani Ani G, Sagar PC. Functional voice disorders and their occurrence in 100 patients of hoarseness as seen in fibreoptic laryngoscopy. Indian J Otolaryngol Head and Neck Surgery 2004;56(21):91-95.
Prakash O, Singh P, Sharma M, Kapoor M. Pattern of benign lesions of larynx. Int J Med Sci Public Health. 2016;5(9):1808.
Saha PP, Jana S. A Clinicopathological Study of Benign Lesions of the Vocal Fold. IOSR J Dent Med Sci. 2017;16(2):9-12.
Chopra H, Kapoor M (1977) Study of benign lesions undergoing microlaryngeal surgery. Indian J Otolaryngol Head Neck Surg 49:276–279.
Ghosh SK, Chattopadhyay S, Bora H, Mukherjee PD. Microlaryngoscopic study of 100 cases of hoarseness of voice. IndJOtolaryngolHead Neck Surg 2001; 53(4):270-72.
Cecatto SB, Costa KS, Garcia RID, Haddad L, Angelico Junior FV, Rapoport P (2002) Vocal cord polyps: clinical and surgical aspects. Rev Bras Otorrinolaringol. 68:543–548
Singh M, Bandyopadhyay S, Gupta SC, Rai A (2002) A study of manifestations of extrapulmonary tuberculosis in the ENT region. Indian J Otolaryngol Head Neck Surg 54:242–245
McGlashen J (2008) Disorders of the voice. In: Hibbert J (ed) Scott-Brown otolaryngology, head and neck surgery, 7th edn. Edward Arnold, London, pp 2192–2210.
Kambic V, Radsel Z, Zargi M, Acko M (1981) Vocal cord polyps: incidence, histology and pathogenesis. J Laryngol Otol 95:609–618
Martin RH, Defaveri J, Domingues MA, Silva RD (2011) Vocal polyps: clinical, morphological and immunohistochemical aspects. J Voice 25:98–106
NunesRB, Behlau M, Nunes MB, Paulino JG. Clinical diagnosis and histological analysis of vocal nodules and polyps. Brazilian J Otorhinolaryngol2013; 79(4), 434-440.
Wallis L, Jackson-Menaldi C, Holland W, Giraldo A. Vocal fold nodule vs. vocal fold polyp: answer from surgical pathologist and voice pathologist point of view. J Voice 2004; 18(1):125-9.
Rosen CA, Murry T, Zinn A, Zullo T, Sonbolian M. Voice Handicap Index change following treatment of voice disorders. J Voice 2000;14: 619–623.